Scientific Cooperation Agreement between the Pasteur Institute and the University of São Paulo under the Tripartite Agreement FIOCRUZ | PASTEUR | USP

“Integrated strategy for the study of infectious agents causing emerging and / or neglected diseases transmitted by national and regional impact vectors”

This new Pasteur / USP partnership is particularly focused on vector-borne emergent and neglected diseases that may cause very complex immune responses and serious anomalies and / or disturbances in the nervous system, consequently impacting animal and public health. These partners are today joining forces in a new Scientific Platform, in the recent "Innovation Center InovaUSP", in spaces strategically designed to implement a novel model for performing scientific research in proximity to the academy. The technological objective of this Platform is to strengthen the development of joint initiatives with a high degree of infrastructures and state-of-the-art equipment, sharing expertise, technologies, and know-how, in view of joint and innovative discoveries of products and processes. This global project is structured around complementary research programs groups of researchers from the two institutions that, in concert through this task force, intend to strengthen their scientific ties by answering questions of medical and veterinary interest in this unique strategic environment. The project aims to achieve the following two main scientific objectives: (i) Generate luminous and fluorescent microorganisms to allow the real-time and detailed analysis of the interaction of these microorganisms with their hosts; (ii) To decipher immune, inflammatory and pathogenetic mechanisms triggered by these infectious agents, notably in the brain; (iii). Build a database from the integration of results generated by Omics, molecular biology and immunology and; (iv). Identify new targets for the development of preventive, diagnostic / prognostic and therapeutic methods.